Medical treatment of epilepsy

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Medical treatment of epilepsy


Mechanisms of action of anti-epileptic drugs

Chapter 25
G Sills

Current anti-epileptic drug targets
Mechanisms of action of existing agents
Implications of mechanisms of actions


Starting anti-epileptic drug treatment: the treatment of newly diagnosed epilepsy

Chapter 26
JW Sander and A Nicholson

In this article:
Diagnosis
The single seizure
Precipitating factors
Adherence to treatment
Prospective risk of epilepsy
Starting treatment
Choice of drug
Problems
Prognosis


The management of chronic epilepsy

Chapter 27
JS Duncan and A Nicholson

In this article:
Anti-epileptic drug treatment in patients with chronic epilepsy
Holistic issues


Overview of established anti-epileptic drugs

Chapter 28
JW Sander

In this article:
Carbamazepine
Clobazam
Clonazepam
Ethosuximide
Gabapentin
Lamotrigine
Phenytoin
Phenobarbitone
Piracetam
Primidone
Sodium valproate (valproic acid)
Tiagabine
Topiramate
Vigabatrin


New anti-epileptic drugs

Chapter 29
JW Sander

In this article:
New AEDs marketed in the UK
AEDs marketed elsewhere
Antiepileptic drugs currently in development


Drug treatment of paediatric epilepsy

Chapter 30
RE Appleton and JH Cross

In this article:
Basic principles
Polytherapy
Drugs available
Which drug?


Pharmacokinetic interactions between antiepileptic drugs

Chapter 31
PN Patsalos


Stopping anti-epileptic drug treatment

Chapter 32
JW Sander

In this article:
Medical factors
Employment
Driving
Leisure pursuits
Contraception and pregnancy


Treatment of tonic-clonic status epilepticus

Chapter 33
MC Walker and SD Shorvon

In this article:
General measures
Treatment of tonic-clonic status epilepticus
Stages in emergency


Treatment of non-convulsive status epilepticus

Chapter 34
MC Walker

In this article:
Diagnosis
Neuronal damage and non-convulsive status epilepticus
Specific forms of non-convulsive status epilepticus
Non-convulsive status epilepticus in coma


Non-pharamcological approaches to seizure control

Chapter 35
PJ Thompson and SA Baxendale

In this article:
Behaviour therapy
Avoidance
Desensitisation
Counter measures
Biofeedback
Operant conditioning
Cognitive therapy
Psychodynamic psychotherapy
Hypnosis
Alternative therapy
Lifestyle focused approaches


Articles are taken from Epilepsy 2009: From Benchside to Bedside, A Practical Guide to Epilepsy. 12th ed (2009). Edited by: JW Sander, MC Walker and JE Smalls. Published by: International League Against Epilepsy (UK Chapter) and The National Society for Epilepsy.
ISBN 978 0 9519552 6 0
ISBN 0 9519552 4 1
There is no copyright but the source should be acknowledged.



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