Research grants

Research grants

Action Medical Research

Project Grant. A Randomised Placebo Controlled Clinical Trial of Light Therapy for Medically Intractable Epilepsy (SA Baxendale, DC Heaney). £43,725. 2009-2011.
Project Grant. Epilepsy genomics in childhood: Finding the cause, directing treatment (SM Sisodiya, JH Cross). £177,240. 2009-2011.

Project Grant. Peripheral nerve excitability in the episodic ataxias (DM Kullmann, H Bostock, MG Hanna). £197,934. 2008-2010.

Alzheimer’s Research Trust

Pilot Grant. Interactions of beta-amyloid and alpha7 nicotinic receptors in hippocampal interneurons (DM Kullmann, I Oren, AD Randall). £29,167. 2009-2010.

Brain Research Trust

Equipment Grant. Implementation and Assessment of Pre-surgical EEG-correlated Functional MRI for Patients with Epilepsy in a Clinical Setting (L Lemieux). £40,500. 2009-2011.

Equipment Grant. Regulation of vesicular exocytosis by calcium channels in individual central synapses (K Volynski). £38,425. 2009.

PhD Studentship Award. Magnetoencephalography in patients with epilepsy: Understanding cognitive dysfunction and localising the epileptogenic zone (N Cashdollar. Supervisors: E Düzel, JS Duncan). £85,909. 2006-2009.

PhD Studentship Award. Manipulation of Neuronal signalling with light-activated ion channels (L Mantoan. Supervisors: DM Kullmann, S Schorge). £91,237. 2008-2011 (with supplementation from the Guarantors of Brain).

Project Grant. Nano-diffusion in the brain extracellular space (DA Rusakov). £52,300. 2008-2009.

Project Grant. Peripheral markers of neuronal excitability in CNS Channelopathies (DM Kullmann, MG Hanna, H Bostock). £34,600. 2008-2009.

Project Grant. Long term prognosis of Epilepsy (A Neligan; Supervisors: JW Sander, SD Shorvon). £67,000. 2009-2010.

CRDC

Project Grant. Synaptic mechanism of action of the novel antiepileptic drug Levetiracetam (K Volynski). . £79,917.00. 2008-2010.

ER-UK

Fellowship Grant. Cell type-specific modulation of tonic GABA(A) receptor-mediated conductances in epilepsy (I Pavlov). £186,864. 2009-2012.

Project Grant. The role of inflammation in brain injury and epileptogenesis following status epilepticus (M Lythgoe, R Scott, D Anthony, MC Walker, D Gadian). £79,937. 2007-2009.

Project Grant. Potassium channels in epilepsy (MC Walker, DM Kullmann, S Schorge). £99,397. 2009-2011.

European Union

European Research Council. InterPlasticity - Long-term synaptic plasticity in interneurons: mechanisms and computational significance (DM Kullmann). £1,875,000. 2009-2014.

6th Framework Programme. PROMEMORIA From cell-cell recognition to memory formation: new strategies for the treatment of dysfunctional plasticity, learning and memory (DA Rusakov, collaborators across Europe). €495,000. 2005-2009.

6th Framework Programme. EPICURE Functional genomics, neurobiology of epilepsy as a basis for new therapeutic strategies (MC Walker, DM Kullmann, S Schorge). €347,000. 2007-2010.

7th Framework Programme. EURIPIDES European Research Initiative to develop imaging probes for early in vivo diagnosis and evaluation of response to therapeutic substances (MJ Koepp, JS Duncan, JW Sander, SM Sisodiya, B Hutton, P Ell, A Lammertsmaa, B Windhorst, O Langer, C Baumgartner, W Loescher, H Potschka, S Noachtar, P Bartenstein, P Ryvlin, A Hammers). €6,994,850. 2008-2012.

Collaborative Project. SPACEBRAIN: Space coding in hippocampo-entorhinal neuronal assemblies (E Moser; Co-ordinator, Trondheim + 6 partners). €3,000,000 (inc. €816,000 for N, Burgess, K Jeffery and J O'Keefe, UCL). 2008-2011.

Henry Smith Charity

Project Grant. Psychiatric outcome of epilepsy surgery and relationship to cognitive function (J. Foong, PJ Thompson). £148,472. 2009-2010.

Human Frontier Science Programme

Research Programme Grant. Glia and extra-synaptic communication in the brain (DA Rusakov, Co-ordinator; International co-PIs: S Oliet, J Diamond NIH, A Semyanov). $1,350,000. 2006-2010.

Medical Research Council

Career Development Award. Calcium channels in evoked neurotransmitter release at individual synapses and neurological disease (K Volynski; Sponsors DM Kullmann, DA Rusakov). £620,000. 2006-2011.

Clinical Research Training Fellowship. Translation of novel imaging techniques into clinical use for patients with epilepsy (G Winston. Supervisor: JS Duncan). £203,200. 2009-2012.

Programme Grant. MR imaging of brain generators in human epilepsy (L Lemieux, PJ Allen, JS Duncan, DR Fish, RC Turner, MC Walker). £1,270,093. 2004-2010.

Project Grant. Alpha7 nicotinic receptor actions on GABAergic transmission. (DM Kullmann). £410,063. 2006-2010.

Project Grant. Probing presynaptic receptor function with two-photon uncaging Ca2+ imaging and photobleaching (DA Rusakov, DM Kullmann, R Scott). £440,000. 2006-2010.

Project Grant. The role of persistent currents generated by sodium channel splicing in neurological disorders (S Schorge, P Jat, DM Kullmann). £450,000. 2007-2010.

Project Grant. Activity-diffusion coupling in neural signalling (DA Rusakov, DM Kullmann, MC Walker).£282,000. 2005-2009.

Project Grant. Post mortem studies in epilepsy: use and curation of a unique UK resource (SM Sisodiya, M Thom, DB Goldstein, PB Crino). £483,813. 2007-2011.

Project Grant. Modulation of neurotransmitter release by cannabinoid receptors at individual cortical synapses (DA Rusakov, DM Kullmann, T Jensen). £599,000. 2009-2013.

Project Grant. Lentiviral potassium channel expression to treat focal neocortical epilepsy (DM Kullmann, S Schorge, MC Walker). £1,008,392. 2009-2012.

Project Grant. Nano-diffusion in the brain: mechanisms and implications examined with time-resolved fluorescence anisotropy imaging (DA Rusakov, K Suhling KCL). £1,130,000. 2009-2013.

Senior Non Clinical Fellowship. Cell and Systems Analysis of Spatial and Episodic Memory (N Burgess). Renewal. £1,433,935. 2006-2011.

Strategic Grant. Seizure prevention via control of neuronal activity (MC Walker, JR Terry, M Richardson, B Krauskopf, M Di Bernardo). £367,948. 2008-2009.

Myasthenia Gravis Association

John Newsom-Davis Fellowship. Presynaptic mechanisms in Lambert-Eaton myasthenic syndrome (DM Kullmann). £180,000. 2008-2011.

National Health and Medical Research Council (Australia)

Project Grant. Genetic and phenotype studies in Gypsies (JW Sander, L Kalaydjieva). AU$621,250. 2006-2010.

National Hospital Development Foundation

Project Grant. Epilepsy text messaging service pilot project (A Linklater). £7,000. 2009-2010.

Tuberous Sclerosis Association UK

Project Grant. Functional consequences of candidate genetic variants determining visual field loss caused by vigabatrin: towards a mechanistic understanding and prediction of field loss (SM Sisodiya, DB Goldstein, J Acheson, JW Sander, P Brown). £108,788. 2008-2011.

UCB Pharma Ltd

Equipment Grant. Contribution for the purchase of an LC-MS System (PN Patsalos). £10,000. 2009-2010.
Project Grant. Epilepsy text messaging service pilot project (A Linklater). £15,000. 2009-10.

Research Fellowship for The retention of lacosamide in chronic epilepsy study. (JW Sander) £150.000. 2009 – 2011.

UCL Business

Proof of concept study of Wearable apnoea detection device (JS Duncan). £50,000. 2009-2011.

UCLH / UCL CBRC

Project Grant. Magnetoencephalography in Epilepsy (FJ Rugg-Gunn, JS Duncan, E Duzel, RJ Dolan). £161,351. 2008-2011.

Project Grant. Optimising presurgical multimodel investigation of patients with chronic refractory epilepsy (MC Walker, P Allen, JS Duncan, E Duzel, D Heaney, D Holdright, M Koepp, M Koltzenburg, L Lemieux, A McEvoy, F Rugg-Gunn, JW Sander, C Scott, S Shorvon, S Sisodiya, S Smith, P Taggart). £180,000. 2008-2012.

Project Grant. Understanding genetic control of brain structure and function: insights and management strategies from inherited eye diseases (SM Sisodiya, AT Moore, D Hunt, F Vargha-Khadem, JS Duncan). £229,568. 2009-2012.

Wellcome Trust

Programme Grant. Integrated structural and functional imaging in epilepsy (JS Duncan, DR Fish, PS Tofts, MJ Koepp, GJ Barker). £1,703,499. 2002-2009.

Programme Grant. The consequences of surgery for temporal lobe epilepsy (JS Duncan, MJ Koepp, PJ Thompson). £1,487,687. 2008-2013.

Programme Grant. Neural basis of spatial memory and navigation (J O'Keefe, N Burgess). Renewal. £990,724. 2007-2012.

Project Grant. Long-term potentiation in hippocampal interneurons: cellular mechanisms (DM Kullmann, DA Rusakov). £240,722. 2006-2009.

Project Grant. The neuroanatomical basis of frontal lobe cognitive dysfunction in frontal lobe and idiopathic generalised epilepsies (MJ Koepp, MP Richardson, JS Duncan, MR Symms, GJ Barker, PJ Thompson, V Kumari). £458,657. 2007-2010.

Project Grant. Regulation of tonic currents through changes in extracellular GABA (MC Walker, A Semyanov, A Linthorst). £259,237. 2008-2011.

Project Grant. Virally-delivered shRNA for Focal Epilepsy (S Schorge, DM Kullmann, MC Walker). £323,861. 2009-2012.

Project Grant. Long-term potentiation in hippocampal interneurons: cellular mechanisms (DM Kullmann, DA Rusakov). £240,722. 2006-2009.

"Genomics of Common Diseases" scheme. Genome wide association studies in partial epilepsies (SM Sisodiya, DB Goldstein, G Avanzini, N Delanty, C Depondt, M Johnson, JW Sander, NW Wood). £1,375,065. 2008-2011.

PhD Studentship (T Akam. Supervisor: DM Kullmann). £121,316. 2007-2010.

Wellcome Trust Senior Research Fellowship in Basic Biomedical Sciences, Renewed. Principles of neurotransmitter signal formation in the brain (DA Rusakov). Renewal. £1,250,114. 2008-2013.